Group: anti-malaria drug.
Dosage and content: syringe 40mg/ml, 80 mg / 1 ml. Artemether in refined coconut oil.
Indication:
Artemether is indicated for the treatment of malaria caused by all kinds of Plasmodium, including severe malaria caused by multi-resistant Plasmodium falciparum
Artemether is a effective drug in treating malaria, but only use artemether when other anti-malaria drug does not work and must take full dose.
Contra- indications: Contraindication are not known clearly.
Pregnancy
Experience on the human are limited, especially in the early stages of pregnancy. No side effects have meaning in 23 children born of mothers who have used artemether in the period of 16th-38th week of pregnancy. Thus drugs can be used for pregnancy has cerebral malaria or malaria in areas may be complicated caused by multi-resistant Plasmodium falciparum
Lactation
Not known how the drug transfer into breast milk. But should stop breastfeeding if the mother is treated with artemether.
ADR:
Using a total dose of 700 mg did not show side effects. Millions of people have used artemether, but no serious harmful effects. Have reported on the changes the test parameters, such as reducing red grid, increased transaminase and changes on electrocardiogram. May occur abdominal pain, nausea, vomiting, diarrhea, and tinnitus. However, these changes are only transient. Have not seen the neurological toxicity in humans.
Dealing with ADR contructions:
The drug dose should be sufficient to protect against recurrence.
When severe malaria, to extend treatment to 7 days.
Dosage and usage
Only used for adults and children over 6 months old. Be severe malaria or complications:
Method 1: Day 1: intramuscular 3.2 mg / kg / day, four days after: 1.6 mg / kg / day.
Method 2: Day 1: intramuscular 3.2 mg / kg / day. After that day intramuscular injection 1.6 mg / kg until the patient can use the pill in oral, swith to use oral or ?nective anti-malaria drugs, but not exceed 7 days.
Only use arthemether once a day. When inject for children, use 1 ml tuberculin syringe, for injecting small doses.
Stability and preservation:
To avoid light, avoid heat, stored at room temperature. If so long in cold temperatures, can be precipitated, but can be melt if left at room temperature. If precipitation does not dissolve completely, must be discarded.
Shelf life:
24 months from the date of manufacture
Incompatibleness
Artemether can be used in combination with other anti - malaria drugs especially with mefloquin.
Overdose and treatment position
Using overdose, need treatment for symptoms of poisoning in the emergency room. There is no specific antidote.
